Difference in triptan effect in patients with migraine and early allodynia

C Lampi, G Huber, S Haas, E Rittberger… - …, 2008 - journals.sagepub.com
… whether in migraine patients with and without aura early treatment with various triptans
leads to differences in pain reduction after 1 h and in modulating cutaneous allodynia. Thirty-six …

Defeating migraine pain with triptans: a race against the development of cutaneous allodynia

R Burstein, B Collins… - Annals of Neurology …, 2004 - Wiley Online Library
… of migraine (baseline), within the first hour of one attack, or at 4 hours from onset of another
attack. Presence or absence of allodynia was determined based on differences between …

Allodynia is associated with initial and sustained response to acute migraine treatment: results from the American Migraine Prevalence and Prevention Study

RB Lipton, S Munjal, DC Buse… - Headache: The …, 2017 - Wiley Online Library
… 24 hours after triptan therapy; in the absence of allodynia, overall PF … early with delayed
treatment of acute attacks in patients with … group against triptan users and to compare unadjusted …

Migraine, allodynia, and implications for treatment

M Schürks, HC Diener - European journal of neurology, 2008 - Wiley Online Library
… of established allodynia, (ii) triptans may abort headache by disrupting … early or as late as
possible after attack onset, did not find a difference in time to freedom from pain and headache

Dihydroergotamine for early and late treatment of migraine with cutaneous allodynia: An open‐label pilot trial

SD Silberstein, WB Young, MM Hopkins… - Headache: The …, 2007 - Wiley Online Library
patient headache free is associated with the absence or presence of cutaneous allodynia at
the time of triptan … of brush allodynia at 8 hours postdose was significantly different between …

Allodynia‐associated symptoms, pain intensity and time to treatment: Predicting treatment response in acute migraine intervention

RK Cady, FG Freitag, NT Mathew… - Headache: The …, 2009 - Wiley Online Library
triptans: (1) treat when headache pain is mild; (2) treat early … of migraine with an oral triptan
when cutaneous allodynia is … The differences in pharmacokinetic properties of oral and …

Clinical benefits of early triptan therapy for migraine

MJA Lainez - Cephalalgia, 2004 - journals.sagepub.com
… Preliminary observations from Burstein and colleagues in migraine patients suggest that the
presence of cutaneous allodynia influences the response to triptan treatment and that early

Efficacy of triptans for the treatment of acute migraines: a quantitative comparison based on the dose-effect and time-course characteristics

M Hou, H Liu, Y Li, L Xu, Y He, Y Lv, Q Zheng… - European Journal of …, 2019 - Springer
Triptans should be included first since they are first line for acute migraines in addition to
their remarkable curative effect and … Presently, there are seven triptans available, including …

The impact of allodynia on the efficacy of almotriptan when given early in migraine: data from the “act when mild” study

S Diaz-Insa, PJ Goadsby, G Zanchin… - International Journal …, 2011 - Taylor & Francis
… that if allodynia is present, the response to triptan therapy is likely to … early or late during a
migraine attack, and concluded that … , the difference in migraine duration in those with allodynia

Early treatment in migraine: how strong is the current evidence?

A Gendolla - Cephalalgia, 2008 - journals.sagepub.com
… the phenomenon of cutaneous allodynia and muscle tenderness (10). Triptans are
believed to act at several different points during the progression of a migraine attack, inhibiting …